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Index > Protein center > Cd14(Gene name) > Rat
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  • Cd14 (Gene name),
  • Monocyte differentiation antigen CD14 (Protein name ),  CD14_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cd14;
    Protein name:
    Monocyte differentiation antigen CD14;
    Alternative:
    Myeloid cell-specific leucine-rich glycoprotein;
    CD:
    CD14;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4.
    Function:
    Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    372
    Sequence:
    50:
    MKLMLGLLLL | PLTLVHASPA | TPEPCELDQD | EESVRCYCNF | SDPQPNWSSA | 
    100:
    FLCAGAEDVE | FYGGGRSLEY | LLKRVDTEAN | LGQYTDIIRS | LPLKRLTVRS | 
    150:
    ARVPTQILFG | TLRVLGYSGL | RELTLENLEV | TGTALSPLLD | ATGPDLNTLS | 
    200:
    LRNVSWATTD | TWLAELQQWL | KPGLKVLSIA | QAHSLNFSCK | QVGVFPALAT | 
    250:
    LDLSDNPELG | EKGLISALCP | HKFPTLQVLA | LRNAGMETTS | GVCSALAAAR | 
    300:
    VPLQALDLSH | NSLRDTAGTP | SCDWPSQLNS | LNLSFTGLEH | VPKGLPAKLS | 
    350:
    VLDLSYNRLD | RKPRPEELPE | VGSLSLTGNP | FLHSESQSEA | YNSGVVIATA | 
    372:
    LSPGSAGLSG | TLALLLGHRL | FV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Monocyte differentiation antigen CD14
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    ELISA Kit for Rat Monocyte differentiation antigen CD14
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    ELISA Kit for Rat Monocyte differentiation antigen CD14
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    ELISA Kit for Rat Monocyte differentiation antigen CD14
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    ELISA Kit for Rat Monocyte differentiation antigen CD14
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    CLIA Kit for Rat Monocyte differentiation antigen CD14
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    U0685h
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    Packing:
    96T
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    CLIA Kit for Rat Monocyte differentiation antigen CD14
    Cat.:
    U0685r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Monocyte differentiation antigen CD14
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Monocyte differentiation antigen CD14
    Cat.:
    U0685b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Monocyte differentiation antigen CD14
    Cat.:
    U0685m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat Monocyte differentiation antigen CD14
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    P0685Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Monocyte differentiation antigen CD14
    Polyclonal Antibody for Rat Monocyte differentiation antigen CD14
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    P0685Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Monocyte differentiation antigen CD14
    Cat.:
    P0685Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Monocyte differentiation antigen CD14
    Monoclonal Antibody for Rat Monocyte differentiation antigen CD14
    Monoclonal Antibody for Rat Monocyte differentiation antigen CD14
    Monoclonal Antibody for Rat Monocyte differentiation antigen CD14
    Monoclonal Antibody for Rat Monocyte differentiation antigen CD14
    Monoclonal Antibody for Rat Monocyte differentiation antigen CD14
    Protein for Rat Monocyte differentiation antigen CD14
    Protein for Rat Monocyte differentiation antigen CD14
    Protein for Rat Monocyte differentiation antigen CD14
    Protein for Rat Monocyte differentiation antigen CD14
    Protein for Rat Monocyte differentiation antigen CD14

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    References
    1. 1.
      "CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells."
      Galea E. , Reis D.J. , Fox E.S. , Xu H. , Feinstein D.L.
      J. Neuroimmunol.64:19-28(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Spleen.
    2. 2.
      "Primary structure of rat CD14 and characteristics of rat CD14, cytokine, and NO synthase mRNA expression in mononuclear phagocyte system cells in response to LPS."
      Takai N. , Kataoka M. , Higuchi Y. , Matsuura K. , Yamamoto S.
      J. Leukoc. Biol.61:736-744(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Expression of CD14 by hepatocytes: upregulation by cytokines during endotoxemia."
      Liu S. , Khemlani L.S. , Shapiro R.A. , Johnson M.L. , Liu K. , Geller D.A. , Watkins S.C. , Goyert S.M. , Billiar T.R.
      Infect. Immun.66:5089-5098(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Prostate.
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